THE OPEP COARSE-GRAINED PROTEIN MODEL: FROM SINGLE MOLECULES, AMYLOID FORMATION, ROLE OF MACROMOLECULAR CROWDING AND HYDRODYNAMICS TO RNA/DNA COMPLEXES
Identifieur interne : 000E02 ( Main/Exploration ); précédent : 000E01; suivant : 000E03THE OPEP COARSE-GRAINED PROTEIN MODEL: FROM SINGLE MOLECULES, AMYLOID FORMATION, ROLE OF MACROMOLECULAR CROWDING AND HYDRODYNAMICS TO RNA/DNA COMPLEXES
Auteurs : Fabio Sterpone [France] ; Simone Melchionna [Italie] ; Pierre Tuffery [France] ; Samuela Pasquali [France] ; Normand Mousseau [Canada] ; Tristan Cragnolini [France] ; Yassmine Chebaro [France] ; Jean-Francois Saint-Pierre [Canada] ; Maria Kalimeri [France] ; Alessandro Barducci [Suisse] ; Yohan Laurin [France] ; Alex Tek [France] ; Marc Baaden [France] ; Phuong Hoang Nguyen [France] ; Philippe Derreumaux [France]Source :
- Chemical Society reviews [ 0306-0012 ] ; 2014.
Abstract
The OPEP coarse-grained protein model has been applied to a wide range of applications since its first release 15 years ago. The model, which combines energetic and structural accuracy and chemical specificity, allows studying single protein properties, DNA/RNA complexes, amyloid fibril formation and protein suspensions in a crowded environment. Here we first review the current state of the model and the most exciting applications using advanced conformational sampling methods. We then present the current limitations and a perspective on the on-going developments.
Url:
DOI: 10.1039/c4cs00048j
PubMed: 24759934
PubMed Central: 4426487
Affiliations:
Links toward previous steps (curation, corpus...)
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Le document en format XML
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Centre Ville, Montréal, Québec, H3C 3J7, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Département de Physique, Université de Montréal, C.P. 6128, succ. 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Centre Ville, Montréal, Québec, H3C 3J7, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Département de Physique, Université de Montréal, C.P. 6128, succ. Centre Ville, Montréal, Québec, H3C 3J7</wicri:regionArea><wicri:noRegion>H3C 3J7</wicri:noRegion></affiliation></author><author><name sortKey="Kalimeri, Maria" sort="Kalimeri, Maria" uniqKey="Kalimeri M" first="Maria" last="Kalimeri">Maria Kalimeri</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Barducci, Alessandro" sort="Barducci, Alessandro" uniqKey="Barducci A" first="Alessandro" last="Barducci">Alessandro Barducci</name><affiliation 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nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Tek, Alex" sort="Tek, Alex" uniqKey="Tek A" first="Alex" last="Tek">Alex Tek</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Baaden, Marc" sort="Baaden, Marc" uniqKey="Baaden M" first="Marc" last="Baaden">Marc Baaden</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Nguyen, Phuong Hoang" sort="Nguyen, Phuong Hoang" uniqKey="Nguyen P" first="Phuong Hoang" last="Nguyen">Phuong Hoang Nguyen</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Derreumaux, Philippe" sort="Derreumaux, Philippe" uniqKey="Derreumaux P" first="Philippe" last="Derreumaux">Philippe Derreumaux</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A6">Institut Universitaire de France, 103 Boulevard Saint-Michel, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut Universitaire de France, 103 Boulevard Saint-Michel, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24759934</idno><idno type="pmc">4426487</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426487</idno><idno type="RBID">PMC:4426487</idno><idno type="doi">10.1039/c4cs00048j</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001636</idno><idno type="wicri:Area/Pmc/Curation">001636</idno><idno type="wicri:Area/Pmc/Checkpoint">000919</idno><idno type="wicri:Area/Ncbi/Merge">002F12</idno><idno type="wicri:Area/Ncbi/Curation">002F12</idno><idno type="wicri:Area/Ncbi/Checkpoint">002F12</idno><idno type="wicri:doubleKey">0306-0012:2014:Sterpone F:the:opep:coarse</idno><idno type="wicri:Area/Main/Merge">000E01</idno><idno type="wicri:Area/Main/Curation">000E02</idno><idno type="wicri:Area/Main/Exploration">000E02</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">THE OPEP COARSE-GRAINED PROTEIN MODEL: FROM SINGLE MOLECULES, AMYLOID FORMATION, ROLE OF MACROMOLECULAR CROWDING AND HYDRODYNAMICS TO RNA/DNA COMPLEXES</title><author><name sortKey="Sterpone, Fabio" sort="Sterpone, Fabio" uniqKey="Sterpone F" first="Fabio" last="Sterpone">Fabio Sterpone</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Melchionna, Simone" sort="Melchionna, Simone" uniqKey="Melchionna S" first="Simone" last="Melchionna">Simone Melchionna</name><affiliation wicri:level="3"><nlm:aff id="A2">Instituto Processi Chimico-Fisici, CNR-IPCF, Consiglio Nazionale delle Ricerche, Roma, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Instituto Processi Chimico-Fisici, CNR-IPCF, Consiglio Nazionale delle Ricerche, Roma</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Tuffery, Pierre" sort="Tuffery, Pierre" uniqKey="Tuffery P" first="Pierre" last="Tuffery">Pierre Tuffery</name><affiliation wicri:level="3"><nlm:aff id="A3">INSERM U973, Université Paris Diderot, Sorbonne Paris Cité, 75013, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>INSERM U973, Université Paris Diderot, Sorbonne Paris Cité, 75013</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Pasquali, Samuela" sort="Pasquali, Samuela" uniqKey="Pasquali S" first="Samuela" last="Pasquali">Samuela Pasquali</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mousseau, Normand" sort="Mousseau, Normand" uniqKey="Mousseau N" first="Normand" last="Mousseau">Normand Mousseau</name><affiliation wicri:level="1"><nlm:aff id="A4">Département de Physique, Université de Montréal, C.P. 6128, succ. Centre Ville, Montréal, Québec, H3C 3J7, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Département de Physique, Université de Montréal, C.P. 6128, succ. Centre Ville, Montréal, Québec, H3C 3J7</wicri:regionArea><wicri:noRegion>H3C 3J7</wicri:noRegion></affiliation></author><author><name sortKey="Cragnolini, Tristan" sort="Cragnolini, Tristan" uniqKey="Cragnolini T" first="Tristan" last="Cragnolini">Tristan Cragnolini</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Chebaro, Yassmine" sort="Chebaro, Yassmine" uniqKey="Chebaro Y" first="Yassmine" last="Chebaro">Yassmine Chebaro</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Saint Pierre, Jean Francois" sort="Saint Pierre, Jean Francois" uniqKey="Saint Pierre J" first="Jean-Francois" last="Saint-Pierre">Jean-Francois Saint-Pierre</name><affiliation wicri:level="1"><nlm:aff id="A4">Département de Physique, Université de Montréal, C.P. 6128, succ. Centre Ville, Montréal, Québec, H3C 3J7, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Département de Physique, Université de Montréal, C.P. 6128, succ. Centre Ville, Montréal, Québec, H3C 3J7</wicri:regionArea><wicri:noRegion>H3C 3J7</wicri:noRegion></affiliation></author><author><name sortKey="Kalimeri, Maria" sort="Kalimeri, Maria" uniqKey="Kalimeri M" first="Maria" last="Kalimeri">Maria Kalimeri</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Barducci, Alessandro" sort="Barducci, Alessandro" uniqKey="Barducci A" first="Alessandro" last="Barducci">Alessandro Barducci</name><affiliation wicri:level="1"><nlm:aff id="A5">Laboratoire de Physique Statistique, Ecole Polytechnique de Lausanne (EPFL), CH-1015 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Laboratoire de Physique Statistique, Ecole Polytechnique de Lausanne (EPFL), CH-1015 Lausanne</wicri:regionArea><wicri:noRegion>CH-1015 Lausanne</wicri:noRegion></affiliation></author><author><name sortKey="Laurin, Yohan" sort="Laurin, Yohan" uniqKey="Laurin Y" first="Yohan" last="Laurin">Yohan Laurin</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Tek, Alex" sort="Tek, Alex" uniqKey="Tek A" first="Alex" last="Tek">Alex Tek</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Baaden, Marc" sort="Baaden, Marc" uniqKey="Baaden M" first="Marc" last="Baaden">Marc Baaden</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Nguyen, Phuong Hoang" sort="Nguyen, Phuong Hoang" uniqKey="Nguyen P" first="Phuong Hoang" last="Nguyen">Phuong Hoang Nguyen</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Derreumaux, Philippe" sort="Derreumaux, Philippe" uniqKey="Derreumaux P" first="Philippe" last="Derreumaux">Philippe Derreumaux</name><affiliation wicri:level="3"><nlm:aff id="A1">Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 rue Pierre et Marie Curie, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A6">Institut Universitaire de France, 103 Boulevard Saint-Michel, 75005, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut Universitaire de France, 103 Boulevard Saint-Michel, 75005, Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j">Chemical Society reviews</title><idno type="ISSN">0306-0012</idno><idno type="eISSN">1460-4744</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P4">The OPEP coarse-grained protein model has been applied to a wide range of applications since its first release 15 years ago. The model, which combines energetic and structural accuracy and chemical specificity, allows studying single protein properties, DNA/RNA complexes, amyloid fibril formation and protein suspensions in a crowded environment. Here we first review the current state of the model and the most exciting applications using advanced conformational sampling methods. We then present the current limitations and a perspective on the on-going developments.</p></div></front></TEI><affiliations><list><country><li>Canada</li><li>France</li><li>Italie</li><li>Suisse</li></country><region><li>Latium</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>Rome</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Sterpone, Fabio" sort="Sterpone, Fabio" uniqKey="Sterpone F" first="Fabio" last="Sterpone">Fabio Sterpone</name></region><name sortKey="Baaden, Marc" sort="Baaden, Marc" uniqKey="Baaden M" first="Marc" last="Baaden">Marc Baaden</name><name sortKey="Chebaro, Yassmine" sort="Chebaro, Yassmine" uniqKey="Chebaro Y" first="Yassmine" last="Chebaro">Yassmine Chebaro</name><name sortKey="Cragnolini, Tristan" sort="Cragnolini, Tristan" uniqKey="Cragnolini T" first="Tristan" last="Cragnolini">Tristan Cragnolini</name><name sortKey="Derreumaux, Philippe" sort="Derreumaux, Philippe" uniqKey="Derreumaux P" first="Philippe" last="Derreumaux">Philippe Derreumaux</name><name sortKey="Derreumaux, Philippe" sort="Derreumaux, Philippe" uniqKey="Derreumaux P" first="Philippe" last="Derreumaux">Philippe Derreumaux</name><name sortKey="Kalimeri, Maria" sort="Kalimeri, Maria" uniqKey="Kalimeri M" first="Maria" last="Kalimeri">Maria Kalimeri</name><name sortKey="Laurin, Yohan" sort="Laurin, Yohan" uniqKey="Laurin Y" first="Yohan" last="Laurin">Yohan Laurin</name><name sortKey="Nguyen, Phuong Hoang" sort="Nguyen, Phuong Hoang" uniqKey="Nguyen P" first="Phuong Hoang" last="Nguyen">Phuong Hoang Nguyen</name><name sortKey="Pasquali, Samuela" sort="Pasquali, Samuela" uniqKey="Pasquali S" first="Samuela" last="Pasquali">Samuela Pasquali</name><name sortKey="Tek, Alex" sort="Tek, Alex" uniqKey="Tek A" first="Alex" last="Tek">Alex Tek</name><name sortKey="Tuffery, Pierre" sort="Tuffery, Pierre" uniqKey="Tuffery P" first="Pierre" last="Tuffery">Pierre Tuffery</name></country><country name="Italie"><region name="Latium"><name sortKey="Melchionna, Simone" sort="Melchionna, Simone" uniqKey="Melchionna S" first="Simone" last="Melchionna">Simone Melchionna</name></region></country><country name="Canada"><noRegion><name sortKey="Mousseau, Normand" sort="Mousseau, Normand" uniqKey="Mousseau N" first="Normand" last="Mousseau">Normand Mousseau</name></noRegion><name sortKey="Saint Pierre, Jean Francois" sort="Saint Pierre, Jean Francois" uniqKey="Saint Pierre J" first="Jean-Francois" last="Saint-Pierre">Jean-Francois Saint-Pierre</name></country><country name="Suisse"><noRegion><name sortKey="Barducci, Alessandro" sort="Barducci, Alessandro" uniqKey="Barducci A" first="Alessandro" last="Barducci">Alessandro Barducci</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= THE OPEP COARSE-GRAINED PROTEIN MODEL: FROM SINGLE MOLECULES, AMYLOID FORMATION, ROLE OF MACROMOLECULAR CROWDING AND HYDRODYNAMICS TO RNA/DNA COMPLEXES
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